Senior Scientist, Process Chemistry

Phlow Corp
Richmond, VA
This role is to provide process chemistry support to Phlow's Continuous Manufacturing R&D lab. The Senior Scientist will possess an in-depth knowledge of process chemistry skills for the development of synthetic routes for drug substances. The candidate will perform multi-step chemical syntheses and product isolation/purification operations in the laboratory either independently or as part of a project team. The candidate will ensure excellence of our process development and technical transfer to Phlow's partners or customers. The candidate will personify Phlow's shared values and culture, both internally and externally. The candidate will work with the highest standards of safety, integrity, transparency, and ethics to create win-win scenarios for patients, customers, partners, and colleagues.

Requirements

Essential Job Duties & Responsibilities

• Provide process chemistry support to Phlow's Continuous Manufacturing R&D lab to ensure the deliverables to customer's projects are met on time and on budget.

• Independently design, synthesize, purify, and analyze chemical intermediates, target compounds, and impurities.

• Maintain accurate, legible, and complete records of all experiments and observations.

• Author progress reports and present scientific results to team members.

• Exhibit a high level of safety awareness and conduct lab operations in a safe manner.

• Contribute to the timely and accurate preparation of regulatory submissions.

• Participate in the ongoing continuous improvements in manufacturing processes resulting in improving product quality, robustness, and cost.

• Collaborate with Analytical Chemistry, EH&S, Engineering, Project Management, Quality Assurance and Regulatory Affairs to ensure strong working relationships with all partners and Phlow employees.

Experience & Qualifications:

• Minimum of 1 year working in related roles in the pharmaceutical industry

• A broad range of functional expertise in modern synthetic organic chemistry, compound purification, spectral analysis/interpretation.

• Experience with searching the chemical literature to evaluate potential solutions to synthetic problems.

• Experience with common analytical techniques such as: HPLC, GC, NMR, UV, LC-MS

• Strong interpersonal and communication skills??

Preferred Qualifications

• Ph.D. with a minimum 1 year of experience, M.S with a minimum 3 years of experience, or B.S. degree with a minimum of 5 years of experience in Organic Chemistry, Pharmaceutical Sciences, or a related scientific field.

• Process chemistry experience with knowledge of API manufacturing processes

• API manufacturing experience on multi-kilogram scale is a plus.

• Knowledge of ICH and cGMP requirements is a plus.

• Experience working for a contract organization (CROs/CMOs/CDMOs) is a plus.

• Experience with the development and implementation of continuous flow manufacturing processes is a plus.

Physical Requirements
  • Constantly required to see to utilize computer screens and monitors to perform job duties including reading & writing, as well as when presenting information and communicating with others.
  • Frequently required to talk or hear to communicate with employees, candidates, vendors, and others, including presenting information in front of groups.
  • Frequently required to reach with arms and hands performing repetitive motions and using finger dexterity to work primarily at a computer keyboard and with a mouse.
  • Frequently required to sit, and frequently required to stand or walk to move around primarily in an office or production environment
  • Frequent time in construction and/or production environments will be required
  • Occasionally lift and/or move up to 10 pounds.
  • Travel anticipated to be approximately 5% with occasional increase in travel demands based on business needs.
About Phlow : Phlow Corp. ("Phlow") is a public benefit pharmaceutical manufacturing company dedicated to reliably supplying affordable, high-quality, essential medicines through U.S. based advanced manufacturing processes. The company manufactures precursor chemical ingredients, active pharmaceutical ingredients (API), and finished pharmaceutical products, domestically for essential medicines critical to the Nation's healthcare. To help ensure the quality, safety, and affordability of pharmaceutical products of strategic importance to?the United States, Phlow utilizes advanced manufacturing platforms, including continuous manufacturing, to provide essential medicines to its customers, health systems, and government partners.

Our shared values at Phlow reflect our personal and professional commitment to serving patients, as well as our colleagues, partners, communities, country, and humankind. When we remain committed to our mission, and genuinely practice each of these shared values, we discover success and significance in all we do. At Phlow, we believe in the shared values of Integrity, Collaboration, Innovation, Lifelong Learning, and Servant Leadership.

Phlow's commitment to diversity includes recognition that our mission is best advanced by the leadership and contributions of colleagues of diverse backgrounds, beliefs, and culture. Recruiting and mentoring staff to create an inclusive organization that reflects our shared values is a priority.

EEO Statement : Phlow provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability or genetics. In addition to federal law requirements Phlow complies with applicable state and local laws governing nondiscrimination in employment in every location in which the organization has facilities. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.
Posted 2025-12-17

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